Anti-tuberculous therapy-induced crystal arthropathy

Mixed crystal-induced arthropathy--a rare finding.

Pyrazinamide induced hyperuricemia in patients taking anti-tuberculous therapy.

OBJECTIVE To record the effect of pyrazinamide on uric acid in patients of tuberculosis. DESIGN Descriptive and observational study. PLACE AND DURATION OF STUDY Chandka Medical College Hospital, Larkana from February 2000 to January 2003. PATIENTS AND METHODS All patients receiving anti-tuberculosis drugs with pyrazinamide were included. Serum uric acid levels were monitored at weeks 0, 2...

Tuberculous spondylitis: abscess drainage after failure of anti-tuberculous therapy.

Spinal tuberculous abscesses usually respond to anti-tuberculous drugs. The purpose of this study was to evaluate the results of surgical drainage after failure of first-line anti-tuberculous drugs. Patients with spinal instability or vertebral collapse were excluded from the study. The authors retrospectively reviewed 11 patients. The operation was successful in all patients. Anterior/posterio...

Frequency of anti-tuberculous therapy-induced hepatotoxicity in patients and their outcome.

BACKGROUND Tuberculosis (TB) is a very common droplet infection especially in the northern areas. If untreated, the disease may be fatal within 5 years in more than half of cases. To study the frequency of anti-tuberculous therapy (ATT) induced hepato-toxicity was the subject of the present hospital based descriptive study. METHOD The study was conducted in Medical Unit, Ayub Teaching Hospita...

Crystal arthropathy of the prosthetic joint

Complications following knee and hip arthroplasty surgery are not uncommon, with features of pain, erythema, warmth and an effusion strongly suggestive of an underlying infective process. Managing septic arthritis in the setting of a prosthetic joint usually requires complex and invasive surgery. A diagnosis of peri-prosthetic crystal arthropathy is often overlooked, however over the last three...